News

Poxel SA, a biopharmaceutical company dedicated to novel treatments for type 2 diabetes, recently announced in a press release that its presentation at the 6th World Congress on Targeting Mitochondria in Berlin, Germany, Oct. 28–30, 2015, entitled “Imeglimin, a New Mitochondria Targeted Agent for Type 2 Diabetes…

Poxel SA, a biopharmaceutical company dedicated to novel treatments for type 2 diabetes, recently announced the presentation of preclinical data on Imeglimin, the company’s first-in-class lead anti-diabetic product, at the 6th World Congress on Targeting Mitochondria held in Berlin, Germany, Oct. 28–30, 2015. Imeglimin, an oral therapeutic agent…

In a new study recently published in the journal Nature Communications, an international research team reported new insights into the molecular changes associated with aging, which reinforced the involvement of mitochondria in the aging process. The study is entitled “The transcriptional landscape of age…

Mitochondrial myopathy is a collective term for diseases related to defective mitochondria in cells. In patients with mitochondrial myopathy, mitochondria are not able to undergo normal oxygen consumption and energy production due to mutations in mitochondrial DNA (mtDNA) or nuclear DNA that affect the mitochondrial machinery of cells. Diseases appear most…

A new study led by researchers at the RIKEN Brain Science Institute revealed a new mouse model for major depressive episodes associated with mitochondrial dysfunction. The study is entitled “Depression-like episodes in mice harboring mtDNA deletions in paraventricular thalamus” and was recently published in the journal…

A team led by scientists from the King’s College London recently published in the journal Proceedings of the National Academy of Sciences the finding of a gene associated with mitochondrial signaling and nerve function, and which could potentially represent a treatment target for patients with neurodegenerative conditions…

In a new study entitled “Defective Human Sperm Cells Are Associated with Mitochondrial Dysfunction and Oxidant Production” researchers investigated if dysfunctional mitochondria were associated with defective sperm, thereby contributing to male infertility. The team’s findings suggest that indeed, low motile sperm is associated with defective mitochondria and…

New evidence suggests that mutations in mitochondrial DNA (mtDNA) may significantly affect fertility and life expectancy, with important differences in male and female organisms. The study, led by PhD student Florencia Camus (School of Biological Sciences at Monash University) and entitled “Single Nucleotides in the mtDNA Sequence Modify Mitochondrial Molecular…

In a recent study sponsored by the National Institutes of Health, a team of scientists developed a new mouse model for Leber hereditary optic neuropathy (LHON), a vision disorder that results from genetic mutations that damage the mitochondria, organelles responsible for producing the body’s energy. The research team determined that…

A new study published in the journal PLOS One suggests a link between mitochondrial dysfunction in important immune cells called leukocytes and the development of chronic obstructive pulmonary disease (COPD). The study is entitled “Leukocyte Mitochondrial DNA Copy Number Is Associated with Chronic Obstructive…