Posts by: Patricia Inacio, PhD

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Researchers found that inherited mutations in the PMPCB gene lead to a wide range of impairments in mitochondria and cause a form of early childhood neurodegenerative disorder in members of ... Read more

March 19, 2018March 19, 2018

New Cellular Pathway Helps Protect Mitochondria During Stress, Study Shows

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A specific branch of cells’ stress-response pathway called unfolded protein response (UPR) may help protect mitochondria, new research shows. This finding suggests that controlling this particular branch may help ... Read more

March 2, 2018March 5, 2018

New Method Improves Delivery of Healthy Mitochondria To Cells Where It Is Dysfunctional, Study Shows

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South Korean researchers have developed a simple way to deliver healthy mitochondria to cells where it is dysfunctional, rescuing the cells’ energy levels and metabolic function. The study, “Delivery ... Read more

February 19, 2018

Manganese Deficiency Underlies Mitochondria Defects in Leigh Syndrome, Other Diseases, Study Finds

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Mutations in the SLC39A8 gene contribute to mitochondria impairments seen in Leigh syndrome by reducing the levels of manganese, a key element that protects against oxidative stress, researchers found. ... Read more

February 5, 2018

Blocking Accumulation of Stress Protein in Mitochondria May Halt PAH Progression, Study Suggests

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The accumulation of the stress-responsive heat shock protein 90 (HSP90) in the mitochondria of certain lung cells is a hallmark of pulmonary arterial hypertension (PAH), and inhibiting HSP90 reversed ... Read more

January 29, 2018January 29, 2018

Compound Mimicking Coenzyme Q10 May Help Protect Neuronal Mitochondria, Study Suggests

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An analog that mimics mitochondrial protein called coenzyme Q10 (CoQ10) has been found to protect neuronal mitochondria from the damaging effects of protein aggregates seen in Alzheimer’s disease. The ... Read more

December 22, 2017December 22, 2017

Genetic Background Influences Number of Mitochondrial Disease-Causing Mutations in Groups of People, Study Says

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The rate of disease-causing mutations in mitochondrial DNA depends on the ethnic background and age of a specific population, researchers report. Disease-causing mutations were lower in European populations and ... Read more

December 18, 2017

Enteral Tube Feeding Improves Nutrition in Kids with Mitochondrial Disease, Review Suggests

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Children affected by mitochondrial diseases who show nutritional deficiencies improve gastrointestinal symptoms, quality of life, and catch up on their development after receiving nutritional support from a feeding tube, ... Read more

November 3, 2017

Targeting Mitochondria Degradation May Help Halt Liver Cancer, Study Suggests

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Researchers have discovered that mitophagy – the selective degradation of damaged mitochondria – allows liver cancer stem cells to survive and contribute to liver tumor growth. Their findings suggest ... Read more

October 25, 2017

Mitochondria May Support Cancer Cell Survival, Study Shows

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Researchers at McGill University in Canada discovered how mitochondria may support cancer cells’ survival even during periods of nutrient starvation. The finding puts mitochondria in the spotlight as regulators of ... Read more

Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Gene Mutation Leads to Early Childhood Neurodegenerative Disorder, Researchers Find

New Cellular Pathway Helps Protect Mitochondria During Stress, Study Shows

New Method Improves Delivery of Healthy Mitochondria To Cells Where It Is Dysfunctional, Study Shows

Manganese Deficiency Underlies Mitochondria Defects in Leigh Syndrome, Other Diseases, Study Finds

Blocking Accumulation of Stress Protein in Mitochondria May Halt PAH Progression, Study Suggests

Compound Mimicking Coenzyme Q10 May Help Protect Neuronal Mitochondria, Study Suggests

Genetic Background Influences Number of Mitochondrial Disease-Causing Mutations in Groups of People, Study Says

Enteral Tube Feeding Improves Nutrition in Kids with Mitochondrial Disease, Review Suggests

Targeting Mitochondria Degradation May Help Halt Liver Cancer, Study Suggests

Mitochondria May Support Cancer Cell Survival, Study Shows

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