Posts by: Patricia Inacio, PhD

News

Researchers report that KH176, under development for the treatment of mitochondrial disease, is well-tolerated when administered to healthy men. The study “KH176 under development for rare mitochondrial disease: a ... Read more

September 22, 2017

Mitobridge Adds NAD+ Modulation as Therapeutic Approach for Mitochondrial Function

News

The therapeutics platform developed by Mitobridge, a biopharmaceutical company developing medicines to improve mitochondria function, will now include modulators of the Nicotinamide Adenine Dinucleotide (NAD+) pathway, the company announced. NAD+ is ... Read more

September 1, 2017

Advanced Imaging Technique Reveals How Mitochondria Incorporate Proteins

News

Researchers at the University of Exeter in England used an advanced imaging technique — electron cryo‐tomography — to show for the first time how proteins are targeted and get incorporated ... Read more

August 28, 2017

Mitochondrial Gene May Be Linked to Obesity in Adulthood, Mouse Study Reports

News

Obesity in adulthood and fatty liver disease may be linked to impaired function of a mitochondrial gene called Ptcd1, a mouse study suggests. The research, “Adult-onset obesity is triggered ... Read more

August 21, 2017August 21, 2017

Blood Test Unveils Mutations Underlying Unknown Mitochondrial Diseases, Australian Study Finds

News

Researchers at Australia’s University of Sydney have developed a blood test capable of identifying mutations in mitochondrial genes. This new test allows a faster diagnosis of rare and often undiagnosed mitochondrial diseases ... Read more

August 18, 2017

Researchers Discover Gene Defect Linked to New Type of Multiple Mitochondrial Dysfunction Syndrome

News

Defects in a gene called iron-sulfur cluster assembly 1 homolog (ISCA1) were found in four children from two unrelated Indian families. These findings suggest that defects within the ISCA1 gene ... Read more

August 9, 2017August 9, 2017

Researchers Develop Method That May Help Diagnose Mitochondrial Diseases

News

Scientists have developed a new strategy for diagnosing mitochondrial diseases and identified the Mrps34 gene as a cause for Leigh syndrome. The study, “Biallelic Mutations in MRPS34 Lead to ... Read more

July 31, 2017July 31, 2017

Mitochondrial Medicine Society Updates Patient Care Guidelines

News

Experts from multiple disciplines have released updated guidelines for the treatment and management of patients with mitochondrial diseases. The review, “Patient care standards for primary mitochondrial disease: a consensus ... Read more

May 5, 2017

Call Issued for Collaborative Studies to Research Pediatric Mitochondrial Disease

News

In an editorial published in the journal Pediatric Neurology, Steven G. Pavlakis, MD, comments on the findings of three studies concerning the many aspects of disease manifestation of children ... Read more

April 10, 2017

Higher Than Normal Mitochondrial DNA Movement May Play Role in Colorectal Cancer

News

Patients with colon and rectal cancer have higher than normal pieces of mitochondrial DNA in their larger DNA portfolio, which is known as nuclear DNA, according to a study. ... Read more