Author Archives: Patricia Inacio, PhD

SPG7 Protein Found to Regulate Mitochondria-Induced Cell Death

In a recent study entitled “SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore”, scientists discovered that the protein SPG7 is the core component of the permeability transition pore (PTP), a structure located in mitochondria membranes, and that it plays a key role…

European Commission Grants Raxone® The First Medicine For Leber’s Hereditary Optic Neuropathy

Santhera Pharmaceuticals, a biopharmaceutical company devoted to the investigation and commercialization of medicines for treating mitochondria and neuromuscular diseases, recently announced that the European Commission granted Raxone® a market authorization in the European Union as the first medicine for the treatment of visual impairment in adolescent and adult patients…

Mitochondria Protein KLF4 Protects Heart Stress-Induced Failure

In a new study entitled “Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis” scientists at the Case Cardiovascular Research Institute report the discovery of a mitochondria protein – Kruppel-like factor 4 (KLF4) – that is crucial for maintaining heart health and protection…