News

Heart mitochondria build power grid networks in a way that allows them to confine disturbances in energy flow to a small region, preventing damage to an entire muscle. The insight may help scientists further understand heart and skeletal muscle function in conditions ranging from heart to mitochondrial disease. Mitochondria, known as…

Researchers from the Shahrekord University of Medical Sciences, in Iran presented the most recent findings of the clinical effects of the hormone melatonin on the development of diseases related to mitochondrial dysfunction, such as diabetes, cancer, gastrointestinal diseases, and conditions related to brain function. The review study, “Melatonin…

The Michael J. Fox Foundation has awarded Great Britain’s Mission Therapeutics and the University of Oxford a grant to test the novel USP30 inhibitor on a range of disease models including Parkinson’s disease. The New York-based foundation announced its grant, whose amount was not disclosed, in a press release on…

Patients with colon and rectal cancer have higher than normal pieces of mitochondrial DNA in their larger DNA portfolio, which is known as nuclear DNA, according to a study. The University of Alabama, Birmingham study, “Migration of mitochondrial DNA in the nuclear genome of colorectal adenocarcinoma,” was published in the…

United Kingdom-based Imanova has received £1 million ($1.2 million U.S.) of strategic Medical Research Council (MRC) funding to clinically evaluate new positron emission tomography (PET) imaging tracers for measuring mitochondrial dysfunction and synaptic loss associated with Alzheimer’s and Parkinson’s diseases. Imanova previously had received a £0.5 million $623,000 U.S.) MRC grant…

GenSight Biologics will present data from studies of its gene therapy GS010 for Leber hereditary optic neuropathy (LHON), a mitochondrial disease, at an upcoming Neuro-Ophthalmology Society conference. According to a press release, the one oral and two poster presentations will be given at the 2017 North American Neuro-Ophthalmology Society‘s (NANOS)…

Co-sponsors The Foundation for Mitochondrial Medicine (FMM) and The United Mitochondrial Disease Foundation (UMDF) have announced that the Southeast Regional Symposium on Mitochondrial Medicine, will be held April 7-8 in Birmingham, Ala. A full day of clinical/medical (CME) sessions will be conducted on Friday, April…

Movement disorders are common among patients with mitochondrial diseases (MIDs). From mild tremors to severe involuntary movements, a broad spectrum of symptoms can be indicative of mitochondrial disease and should prompt an investigation as a possible diagnosis. Many people have the genetic mutations associated with MID development. They can occur in mitochondrial…

The United Kingdom has issued its first license for research that involves women with mitochondria disease receiving donated egg components so they can produce healthy children. Newcastle University researchers will use the U.K. Human Fertilisation and Embryology Authority (HFEA) license to study mitochondrial replacement in 25…

Iranian doctors have shared the case of a 14-year-old girl who developed and died of Leigh syndrome (LS) after suffering a head trauma in school. Their study, “Head Trauma as a Precipitating Factor for Late-onset Leigh Syndrome: A Case Report,” appeared in the journal Emergency. LS, a rare genetic disorder associated…