Posts by: Alice Melão

News

Mitochondrial DNA can react with certain chemicals in the body to produce compounds that trigger genetic mutations — and the mutations can lead to mitochondrial disease, a study reports. ... Read more

March 5, 2018

Potential Gene Therapy May Improve Survival in MNGIE Patients, Mouse Study Suggests

News

A gene therapy designed to correct the underlying defect that causes mitochondrial neurogastrointestinal encephalomyopathy (MNGIE) could potentially improve survival in patients with the disease, a mouse study suggests. The ... Read more

February 28, 2018

Gene Therapy GS010 Is Safe, Well Tolerated by LHON Patients in Phase 1/2 Trial

News

Phase 1/2 trial long-term clinical data on GS010 showed that it is safe and can improve visual acuity in patients with Leber hereditary optic neuropathy (LHON), a mitochondrial disease ... Read more

February 12, 2018

Distinct and New Mitochondrial Disease Seen in Children with Certain PARS2 Mutations in Study

News

Researchers are suggesting that genetic variants of the PARS2 gene are responsible for an entirely new mitochondrial disease, one with distinctive clinical and molecular patterns. Their findings were reported in “Clinical ... Read more

February 2, 2018

Neurovive’s Investigative Compound NV556 Shows Promise to Treat Mitochondrial Myopathy in Preclinical Study

News

NeuroVive Pharmaceutical AB’s investigative compound NV556 holds therapeutic potential for the treatment of mitochondrial myopathy, according to recent data of a preclinical study. Conducted in collaboration with researchers at Karolinska ... Read more

January 19, 2018

Oscillatory Vibration Training Known as SAVT Can Improve Muscle Power in Mitochondrial Disease Patients, Study Shows

News

Side alternating vibration training (SAVT), which uses a vibrating platform to simulate exercise, can improve muscle power in patients with mitochondrial diseases, according to a study published in Archives ... Read more

December 13, 2017December 13, 2017

Mitochondria DNA Seen to Be Complex, Vary in Speed of Mutations Between People and Mice in Study

News

Mitochondria genetics may be more complex than previously thought, with new research reporting that DNA content can vary significantly among different mitochondria within a single cell, and between mice ... Read more

December 4, 2017

NeuroVive Selects Compound from NVP015 Program for Preclinical Studies in Mitochondrial Disorders

News

NeuroVive Pharmaceutical has made significant advances in its NVP015 program for mitochondrial diseases with the identification of a lead compound to develop in preclinical studies. Preliminary analyses in experimental ... Read more

November 22, 2017November 22, 2017

Low Coenzyme Q Is Common Among Genetic Models of Mitochondrial Dysfunction, Study Finds

News

Defective cellular energy production by mitochondria can result from abnormal expression of enzymes involved in the synthesis of the essential co-factor coenzyme Q, a study with mice revealed. This ... Read more

November 20, 2017

Patent Likely to Be Issued to Mitochon for Mitochondria-targeted Therapies

News

The U.S. Patent and Trade Mark Office (USPTO) sent a notice of allowance — meaning it intends to issue a patent — to Mitochon Pharmaceuticals regarding the clinical development of its ... Read more

Posts by: Alice Melão

Alice Melão

Mitochondrial DNA Reaction Can Lead to Mutations That Cause Disease, Study Reports

Potential Gene Therapy May Improve Survival in MNGIE Patients, Mouse Study Suggests

Gene Therapy GS010 Is Safe, Well Tolerated by LHON Patients in Phase 1/2 Trial

Distinct and New Mitochondrial Disease Seen in Children with Certain PARS2 Mutations in Study

Neurovive’s Investigative Compound NV556 Shows Promise to Treat Mitochondrial Myopathy in Preclinical Study

Oscillatory Vibration Training Known as SAVT Can Improve Muscle Power in Mitochondrial Disease Patients, Study Shows

Mitochondria DNA Seen to Be Complex, Vary in Speed of Mutations Between People and Mice in Study

NeuroVive Selects Compound from NVP015 Program for Preclinical Studies in Mitochondrial Disorders

Low Coenzyme Q Is Common Among Genetic Models of Mitochondrial Dysfunction, Study Finds

Patent Likely to Be Issued to Mitochon for Mitochondria-targeted Therapies

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