Posts by: Alice Melão

GenSight Biologics has completed enrollment in a second Phase 3 clinical trial of GS010 as a treatment for the mitochondria eye disease Leber’s Hereditary Optic Neuropathy, or LHON. Both trials are ... Read more

July 28, 2017

Epilepsy Therapies Can Worsen Some Mitochondrial Disorders, Experts Warn

News

Epilepsy is a common manifestation of mitochondrial disorders for about half of the people with the energy-production malfunction. In most cases, doctors can use epilepsy therapies to treat epilepsy stemming ... Read more

July 26, 2017July 26, 2017

Phase 2/3 Trial of Elamipretide to Treat Barth Syndrome Now Enrolling Patients

News

A Phase 2/3 clinical trial of elamipretide, a potential treatment for a rare mitochondrial disease known as Barth syndrome, is now enrolling patients, the therapy’s developer, Stealth BioTherapeutics, announced. The TAZPOWER study ... Read more

July 7, 2017July 7, 2017

First Participant Enrolled in Phase 1 Clinical Trial of KL1333 for Mitochondria Diseases

News

Korean researchers have enrolled the first participant in a Phase 1 clinical trial of KL1333 as a treatment for genetic mitochondrial diseases such as MELAS and Kearns-Sayre syndrome. The healthy participant ... Read more

June 30, 2017

Elamipretide Shows Therapeutic Potential for Primary Mitochondrial Myopathy in Latest Trial Results

News

The investigational drug elamipretide has therapeutic potential to improve the physical capacity of patients with primary mitochondrial myopathy (PMM), according to the latest results of the Phase 2 MMPOWER-2 study. ... Read more

May 26, 2017May 26, 2017

Researchers Review Link Between Renal Disease and Mitochondrial Disorders

News

Kidney involvement in primary mitochondrial disorders (MIDs) is more frequent than anticipated and often is an important factor in the outcome of those with MIDs, a recent review found. The ... Read more

May 15, 2017May 15, 2017

Mitochondrial Genetics Pioneer Douglas Wallace Awarded Prestigious Franklin Medal

News

Douglas C. Wallace, PhD, a researcher at Children’s Hospital of Philadelphia (CHOP), was awarded the 2017 Benjamin Franklin Medal in Life Science for his contributions to the understanding of ... Read more

April 28, 2017

Investigational Therapy SkQ1 Shows Vision Benefits in LHON Patients, Russian Study Finds

News

Use of eye drops to deliver an investigational compound called SkQ1 can help reduce the central vision symptoms of patients with mitochondrial disease Leber’s Hereditary Optic Neuropathy (LHON), results ... Read more

April 24, 2017

GenSight Biologics’ Gene Therapy Candidate May Help Vision Loss in LHON Patients

News

An investigational gene therapy, GS010, is showing some promise in helping people who recently began to lose their vision due to Leber’s hereditary optic neuropathy (LHON), according to data from an ... Read more

April 17, 2017

Researchers Review Melatonin’s Therapeutic Potential for Mitochondrial Dysfunction-related Diseases

News

Researchers from the Shahrekord University of Medical Sciences, in Iran presented the most recent findings of the clinical effects of the hormone melatonin on the development of diseases related ... Read more