Posts by: Alice Melão

News

Phase 1/2 trial long-term clinical data on GS010 showed that it is safe and can improve visual acuity in patients with Leber hereditary optic neuropathy (LHON), a mitochondrial disease ... Read more

February 12, 2018

Distinct and New Mitochondrial Disease Seen in Children with Certain PARS2 Mutations in Study

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Researchers are suggesting that genetic variants of the PARS2 gene are responsible for an entirely new mitochondrial disease, one with distinctive clinical and molecular patterns. Their findings were reported in “Clinical ... Read more

February 2, 2018

Neurovive’s Investigative Compound NV556 Shows Promise to Treat Mitochondrial Myopathy in Preclinical Study

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NeuroVive Pharmaceutical AB’s investigative compound NV556 holds therapeutic potential for the treatment of mitochondrial myopathy, according to recent data of a preclinical study. Conducted in collaboration with researchers at Karolinska ... Read more

January 19, 2018

Oscillatory Vibration Training Known as SAVT Can Improve Muscle Power in Mitochondrial Disease Patients, Study Shows

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Side alternating vibration training (SAVT), which uses a vibrating platform to simulate exercise, can improve muscle power in patients with mitochondrial diseases, according to a study published in Archives ... Read more

December 13, 2017December 13, 2017

Mitochondria DNA Seen to Be Complex, Vary in Speed of Mutations Between People and Mice in Study

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Mitochondria genetics may be more complex than previously thought, with new research reporting that DNA content can vary significantly among different mitochondria within a single cell, and between mice ... Read more

December 4, 2017

NeuroVive Selects Compound from NVP015 Program for Preclinical Studies in Mitochondrial Disorders

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NeuroVive Pharmaceutical has made significant advances in its NVP015 program for mitochondrial diseases with the identification of a lead compound to develop in preclinical studies. Preliminary analyses in experimental ... Read more

November 22, 2017November 22, 2017

Low Coenzyme Q Is Common Among Genetic Models of Mitochondrial Dysfunction, Study Finds

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Defective cellular energy production by mitochondria can result from abnormal expression of enzymes involved in the synthesis of the essential co-factor coenzyme Q, a study with mice revealed. This ... Read more

November 20, 2017

Patent Likely to Be Issued to Mitochon for Mitochondria-targeted Therapies

News

The U.S. Patent and Trade Mark Office (USPTO) sent a notice of allowance — meaning it intends to issue a patent — to Mitochon Pharmaceuticals regarding the clinical development of its ... Read more

November 8, 2017November 8, 2017

Preclinical Studies Show MA-0217 Has Potential to Improve Mitochondria Activity, Kidney Function

News

Mitobridge’s investigative PPARδ modulator MA-0217 has been shown to improve mitochondria activity and kidney function in animal models of acute kidney injury. The findings were the subject of two ... Read more

October 30, 2017

Device Detects Heart-related Mitochondrial Function in Real Time

News

Boston Children’s Hospital researchers have developed a device that can detect real-time oxygen levels in mitochondria and predict the effect those levels will have on organs. Their study dealt specifically ... Read more

Posts by: Alice Melão

Alice Melão

Gene Therapy GS010 Is Safe, Well Tolerated by LHON Patients in Phase 1/2 Trial

Distinct and New Mitochondrial Disease Seen in Children with Certain PARS2 Mutations in Study

Neurovive’s Investigative Compound NV556 Shows Promise to Treat Mitochondrial Myopathy in Preclinical Study

Oscillatory Vibration Training Known as SAVT Can Improve Muscle Power in Mitochondrial Disease Patients, Study Shows

Mitochondria DNA Seen to Be Complex, Vary in Speed of Mutations Between People and Mice in Study

NeuroVive Selects Compound from NVP015 Program for Preclinical Studies in Mitochondrial Disorders

Low Coenzyme Q Is Common Among Genetic Models of Mitochondrial Dysfunction, Study Finds

Patent Likely to Be Issued to Mitochon for Mitochondria-targeted Therapies

Preclinical Studies Show MA-0217 Has Potential to Improve Mitochondria Activity, Kidney Function

Device Detects Heart-related Mitochondrial Function in Real Time

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