Posts by: Jose Marques Lopes, PhD

News

Khondrion’s mitochondrial disease treatment candidate KH176 has potential to be effective in a broad range of disorders, a new study reports. The research, “KH176 Safeguards Mitochondrial Diseased Cells from ... Read more

May 11, 2018May 11, 2018

Multiple Consultations, Tests and Misdiagnoses Mark Mitochondrial Patients ‘Odyssey,’ Survey Finds

News

People with mitochondrial disease typically can visit on average eight different doctors, and undergo multiple tests before finally getting an accurate diagnosis, a patients’ survey reports. The study reporting ... Read more

April 20, 2018April 20, 2018

#AAN2018 – Mutation in USMG5 Gene Causes Leigh Syndrome, Study Shows

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Researchers found that a mutation in the USMG5 gene causes Leigh syndrome and deficient energy production in cells. This is the first evidence linking alterations in this gene to ... Read more

April 13, 2018April 13, 2018

Some Antioxidants Show Benefits in Models of Mitochondrial Disease, Study Reports

News

The antioxidants vitamin E and N-acetylcysteine (NAC) prolonged survival and protected against brain damage in models of mitochondrial disease, a study shows. The compounds will now be tested in clinical ... Read more

March 23, 2018March 23, 2018

Abnormal Protein Interaction Impairs Mitochondrial Function, May Lead to Neurodegenerative Disorders, Study Suggests

News

The normal interaction between two key members of the same mitochondrial protein family is essential to maintain proper energy production and prevent oxidative damage associated with neurodegenerative diseases, Wayne ... Read more

March 7, 2018

Phase 2 Trial Finds Possible Benefits of Omaveloxolone to Mitochondrial Function at Set Dose

News

A potential oral treatment of mitochondrial myopathies called omaveloxolone (RTA 408) appears to improve the mitochondrial function of patients at an optimal dose of 160 mg, top-line data from a ... Read more

January 17, 2018

Study Shows How DNA Mutations in Healthy Mothers May Lead to Severe Mitochondrial Disease in Children

News

A new U.K. study shows why mitochondrial disease can occur in previously healthy families. The research, “Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos,” ... Read more

January 15, 2018

Nutritional Supplements for Mitochondrial Diseases Need Scientific Validation, Experts Contend

News

The use of vitamins and other nutritional supplements to treat mitochondrial diseases needs to be scientifically validated, a study contends. The research, “Nutritional Interventions for Mitochondrial OXPHOS Deficiencies: Mechanisms and Model Systems,” ... Read more

August 25, 2017August 25, 2017

Mitochondria DNA Variation Could Lead to Autism, New Study Suggests

News

Variations in mitochondria DNA, the cellular powerhouses responsible for energy production, could lead to the development of autism, a new study suggests. The study, “Association Between Mitochondrial DNA Haplogroup Variation ... Read more

May 31, 2017May 31, 2017

New Database May Help Diagnose and Predict Outcomes of Mitochondrial Diseases

News

A new tool to help in the diagnosis and outcome prediction of mitochondrial disease has been created by researchers from the U.S. and Finland, according to a study. Findings ... Read more

Posts by: Jose Marques Lopes, PhD

Jose Marques Lopes, PhD

Mitochondrial Disease Treatment Candidate KH176 Shows Potential, Study Finds

Multiple Consultations, Tests and Misdiagnoses Mark Mitochondrial Patients ‘Odyssey,’ Survey Finds

#AAN2018 – Mutation in USMG5 Gene Causes Leigh Syndrome, Study Shows

Some Antioxidants Show Benefits in Models of Mitochondrial Disease, Study Reports

Abnormal Protein Interaction Impairs Mitochondrial Function, May Lead to Neurodegenerative Disorders, Study Suggests

Phase 2 Trial Finds Possible Benefits of Omaveloxolone to Mitochondrial Function at Set Dose

Study Shows How DNA Mutations in Healthy Mothers May Lead to Severe Mitochondrial Disease in Children

Nutritional Supplements for Mitochondrial Diseases Need Scientific Validation, Experts Contend

Mitochondria DNA Variation Could Lead to Autism, New Study Suggests

New Database May Help Diagnose and Predict Outcomes of Mitochondrial Diseases

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