Posts by: Joana Carvalho

News

Symptoms vary greatly among people with mitochondrial disease linked to any one of the many mutations evident in the MT-ATP6 gene, a study found, and its researchers call for better tests ... Read more

May 31, 2019May 31, 2019

Reneo Pharmaceuticals Raises $50M to Support Development of Therapies for Mitochondrial Diseases

News

Reneo Pharmaceuticals has raised $50 million to support the development of therapies for mitochondrial diseases associated with defects in cells’ metabolism and energy production. The company’s fundraising includes contributions ... Read more

February 8, 2019February 8, 2019

Topline Results Announced for Phase 3 Trial Testing GS010 in LHON Patients

News

GenSight Biologics annnounced the topline results of a Phase 3 clinical trial for GS010, a gene therapy designed to improve vision acuity in patients with Leber hereditary optic neuropathy (LHON), ... Read more

January 4, 2019January 4, 2019

AOX Enzyme May Alleviate Symptoms of Mitochondrial Disease, Mouse Study Shows

News

Researchers found an enzyme called alternative oxidase (AOX) that is able to bypass part of the mitochondrial respiratory chain (MRC) and alleviate symptoms of mitochondrial cardiomyopathy in a mouse ... Read more

December 14, 2018December 14, 2018

GS010 Improves Visual Acuity, Quality of Life in LHON Patients, Phase 3 Trial Shows

News

GS010, a gene therapy developed by GenSight Biologics, improves visual acuity and quality of life in patients with Leber hereditary optic neuropathy (LHON), a rare genetic mitochondrial disease that causes ... Read more

August 10, 2018August 10, 2018

Women with Mitochondrial Disease More Prone to Pregnancy Complications, Study Shows

News

Women with mitochondrial disease or mitochondrial dysfunction are more susceptible to complications during pregnancy, and their newborns are more likely to have congenital defects, a retrospective study shows. The study, ... Read more