Mitochondrial Calcium Uniporter Described for First Time by Researchers

Researchers in Shanghai and the U.S. have unveiled a new cellular structure — the mitochondrial calcium uniporter (MCU), which supports cellular energy production  — using two lab techniques, nuclear magnetic resonance and electron microscopy (EM). The study,  “Architecture of the Mitochondrial Calcium Uniporter,“ appeared in the journal Nature. Mitochondria…

CHOP Researchers Restore Cellular Energy Signals, Offering Possibility of Treating Mitochondrial Diseases

Mitochondrial disorders are complex conditions for which few treatments are available. Now, using microscopic worms, researchers at The Children’s Hospital of Philadelphia (CHOP), are researching if existing human drugs aimed at improving metabolism and restore shortened lifespans, can open the opportunity for human clinical trials on innovative therapies for these…