News

the powerhouse of the cell Irving, Texas based Reata Pharmaceuticals, whose mission is to translate innovative research into breakthrough medicines for difficult-to-treat diseases that have significant unmet needs, recently announced the enrollment of their first patient into MOXIe, their Phase 2 clinical study examining the safety, tolerability,…

A collaboration between researchers from Leeds’ St. James’s University Hospital, University College London (UCL) and the Institute of Child Health (UCL) identified a gene mutation affecting mitochondrial calcium (Ca2+) levels in individuals with muscular disease (myopathy), learning and movement deficits. The study included data collected by the UK10K Consortium and is…

Researchers from the University of Helsinki recently found that a vitamin B3 form might be effective in attenuating the progression of mitochondrial myopathy. The study is published in the journal EMBO Molecular Medicine. Mitochondrial disorders are caused by respiratory chain deficiency (RCD) and are the most usual…

Mitochondria, the true energy power plants of cellular activity, play a vital role in energy production and in several other essential cellular processes, including lipid and amino acid metabolism, the urea cycle, iron sulfur cluster assembly, iron homeostasis and cell death. In their normal function, mitochondria are able to release…

A recent case report of a patient with acute kidney injury who was later diagnosed with mitochondrial myopathy, titled “Recurrent episodic acute kidney injury as presenting manifestation of mitochondrial myopathy,” is published in the Indian Journal of Nephrology. Mitochondrial cytopathies (MC) are a rare…

A recent controversial decision to legalize “three parent babies” in the United Kingdom has led researchers to believe that they may have found a solution for heading off genetically transferred Mitochondrial Diseases from Mother to fetus. A new study from researchers at the Hospital Clinic of Barcelona in Spain, however,…

Stealth BioTherapeutics, a biopharmaceutical company developing treatments for rare, mitochondria-related diseases, recently announced the initiation of a new clinical study of Bendavia for the treatment of Mitochondrial Myopathy (MM). Mitochondrial Myopathy (MM) is rare genetic condition that affects the mitochondria, a cell’s “center” responsible for maintaining the body’s energy, causing progressive muscle weakness.

As part of its ongoing effort to improve mitochondrial disease patient care, MitoAction — a nonprofit organization dedicated to improving the quality of life for children, adults, and families living with mitochondrial disease through support, education, outreach, advocacy, and clinical research initiatives — in collaboration with the organization’s Medical Advisory Committee…

A new international study by scientists at the University of Granada (UGR) in Spain, the University of Wisconsin-Madison, Columbia University in New York, and Rutgers, The State University of New Jersey, has uncovered new data on the coenzyme Q10 (CoQ10), a molecule which is normally synthesized within an organism’s own…