Get regular updates to your inbox.
Muscle disorders (myofibrillar myopathies) can sometimes be caused by genetic mutations in genes related to proteins in muscle bands, but other times, myofibrillar myopathies are caused by mitochondrial dysfunction. According to a research team from the Departments of Neurology and Pathology at Technische Universität Dresden in Germany, different subtypes of…
A study recently published in the journal Diagnostic Pathology revealed a new potential mitochondrial biomarker for colorectal cancer. The study is entitled “Mitochondrial A12308G alteration in tRNA Leu (CUN) in colorectal cancer samples” and was conducted by researchers at Kuwait University in Kuwait…
A new study led by researchers at the Salk Institute in California recently discovered an unexpected association between a longevity hormone, fat metabolism and mitochondrial disease in mice. The study was published in the journal Proceedings of the National Academy of Sciences (PNAS) and is entitled…
A study recently published in the journal Human Molecular Genetics revealed a novel promising therapeutic approach for human mitochondrial diseases based on findings in human cells and animal models. The study is entitled “Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease” and…
A new study recently published in the renowned journal Nature revealed a breakthrough on combined stem cell and gene therapies for the treatment of mitochondrial diseases. The study is entitled “Metabolic rescue in pluripotent cells from patients with mtDNA disease” and was led by…
Irving, Texas-based Reata Pharmaceuticals has just announced the enrollment of the first patient in the company’s Phase II MOTOR clinical trial. This study will seek to determine the safety, tolerability and efficacy of Reata’s experimental RTA 408 Oral Capsules as a potential treatment for mitochondrial myopathies (MM). RTA-408 works to improve mitochondrial…
A study recently published in the journal Neurobiology of Aging revealed that the degeneration of the eye’s retina is linked to a mitochondrial dysfunction. The study is entitled “Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but…
Researchers have discovered a specific genetic mutation responsible for a mitochondrial disease observed in mice that quickly ages nine month-old specimens that present with osteoporosis, thinning grey hair, infertility, poor hearing, heart problems and lost weight. The mice carry this disease from birth, but researchers have also found that some harness a “secret weapon” that temporarily…
In a recent review published in the J0urnal of Lifestyle Medicine, a researcher from Korea examined the current literature available about the effect of statins in the skeletal muscle, and the role of exercise in this mechanism. Statins are a class of drugs used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase that…
Santhera Pharmaceuticals, a Swiss specialty pharmaceutical company, recently announced that the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended granting marketing authorization for Raxone (idebenone) to treat the visual impairment found in adult and adolescent patients who suffer from LHON. LHON is a…
Get regular updates to your inbox.