Author Archives: Patricia Silva, PhD

A team led by researchers at Tohoku University Graduate School of Medicine in Japan recently discovered a compound able to improve the survival of cells from patients with mitochondrial diseases, offering a new potential therapeutic approach. The study is entitled “Mitochonic Acid 5 (MA-5), a Derivative…

A study recently published in the journal Diagnostic Pathology revealed a new potential mitochondrial biomarker for colorectal cancer. The study is entitled “Mitochondrial A12308G alteration in tRNA Leu (CUN) in colorectal cancer samples” and was conducted by researchers at Kuwait University in Kuwait…

A new study led by researchers at the Salk Institute in California recently discovered an unexpected association between a longevity hormone, fat metabolism and mitochondrial disease in mice. The study was published in the journal Proceedings of the National Academy of Sciences (PNAS) and is entitled…

A study recently published in the journal Human Molecular Genetics revealed a novel promising therapeutic approach for human mitochondrial diseases based on findings in human cells and animal models. The study is entitled “Inhibiting cytosolic translation and autophagy improves health in mitochondrial disease” and…

A new study recently published in the renowned journal Nature revealed a breakthrough on combined stem cell and gene therapies for the treatment of mitochondrial diseases. The study is entitled “Metabolic rescue in pluripotent cells from patients with mtDNA disease” and was led by…

A study recently published in the journal Neurobiology of Aging revealed that the degeneration of the eye’s retina is linked to a mitochondrial dysfunction. The study is entitled “Mitochondrial decline precedes phenotype development in the complement factor H mouse model of retinal degeneration but…

A study recently published in the journal Frontiers in Genetics reported on a case report of a man with a new mitochondrial disease associated with the desmin (DES) gene. The study is entitled “Desmin common mutation is associated with multi-systemic disease manifestations and depletion of mitochondria…

Researchers at Newcastle University in the United Kingdom recently published in the journal Scientific Reports a new technique to determine genetic deletions in mitochondrial DNA that are relevant in the context of mitochondria-related diseases. The study is entitled “Triplex real-time PCR – an…

Researchers at the University Hospital Münster and the Robert-Bosch-Krankenhaus in Germany recently revealed that patients with different mitochondrial myopathies can exhibit different disease related cardiac phenotypes. The study was recently published in the Journal of Cardiovascular Magnetic Resonance and is entitled “Characteristic…

NeuroVive Pharmaceutical AB, a company focused on the treatment of acute conditions linked to mitochondria, recently announced that its investigational product CicloMulsion® did not meet the primary clinical endpoint in the phase III CIRCUS trial in patients who have experienced a particular type of heart attack called ST-segment elevation…