Author Archives: Magdalena Kegel

Scientists at the University of Pennsylvania’s Perelman School of Medicine discovered that depletion of the mitochondrial factor NAD (nicotinamide adenine di-nucleotide) which helps maintain muscle function and endurance, ramps up muscle breakdown as mice age — a development that can be reversed by giving mice over-the-counter NAD-increasing supplements. Researchers now suggest…

A severe case of mitochondrial disease, caused by mutations in the FBXL4 gene, was confirmed by sequencing the coding parts of the genes of an infant born more than three months premature. The study, “Polyhydramnios and cerebellar atrophy: a prenatal presentation of mitochondrial encephalomyopathy caused by mutations…

While research into the genetic condition Wolfram syndrome has long focused on a cellular component called the endoplasmic reticulum, researchers in Estonia widened their view, and discovered that mitochondria are key contributors to the disease. In addition to advancing an understanding of this syndrome, the study, “Role of Mitochondrial Dynamics in…

In what could be deemed a historic discovery, researchers at the University of California, Davis, have untangled how the process of mitochondrial DNA division is organized, a process linked to the division and later distribution of mitochondria within cells. The study “ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division…

Looking no more eye-catching than a tanning bed, THOR Photomedicine’s Whole Body Light Pod NovoTHOR, capable of improving mitochondrial function, was named the Invention of the Year at the recent Elite Sports Rehabilitation Expo 2016. While the device is new, the method — using low-intensity laser to improve tissue healing…

Changes in the metabolism of mitochondria contribute to adaptations that the immune system makes when encountering bacteria, alive or dead, according to new research published in the journal Nature Immunology. According to a press release, the findings described in the study “Mitochondrial respiratory-chain adaptations in…

MitoMedical, which specializes in supplements for mitochondrial dysfunction, has  launched a public education initiative to help parents of children with mitochondrial problems to learn more about how brain conditions, such as autism, might arise when mitochondria are not working properly. As part of the initiative, MitoMedical released an educational webinar…

Researchers at the University of Granada in Spain developed a new carrier system for the delivery of gene therapy to cells derived from a mouse model of Coenzyme Q10 (CoQ10) deficiency, a mitochondrial condition leading to brain damage. The study, “Gene Therapy Corrects Mitochondrial Dysfunction in Hematopoietic…

A study confirming genetic diagnoses of mitochondrial disease suggests that a new method is a reliable tool for identifying genetic mutations that cause mitochondrial disease in children and infants and for increasing early treatment. The method uses whole exome sequencing – a screening of all genome coding parts (a person’s unique set of genetic instructions.)…

The Wellcome Trust Centre for Mitochondrial Disease has published strong evidence supporting a new in vitro fertilization (IVF) procedure that allows for mitochondrial replacement — lowering the risk of babies being born with inherited mitochondrial mutations. The findings, reported in the journal Nature, represent a huge step forward for research into mitochondrial…